How to Know if TMS Therapy is Right for You

Dr. Irene Pedraza • January 30, 2026
Quick Summary / TL;DR

How to tell if TMS could be a next step

A non-invasive, medication-free option often considered when antidepressants haven’t brought enough relief—or side effects make treatment hard to tolerate.

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Signs TMS may be a fit

  • Medication hasn’t helped enough
    After one or more trials at appropriate dose & duration.
  • Side effects are getting in the way
    Weight changes, brain fog, sexual side effects, emotional “blunting.”
  • You want an outpatient, non-sedating option
    Awake during treatment; resume normal activities after.

Typical timeline

  • Weeks 2–4: subtle improvements may start.
  • 6–8 weeks: common full course length.
  • Builds gradually: benefits are cumulative.

What it feels like

  • Tapping/knocking sensation at the treatment area.
  • No anesthesia —you’re awake the whole time.
  • Back to your day right after the session.

If you’ve been living with depression for a long time and haven’t had success with certain treatments, it’s completely normal to wonder when it’s time to consider something different.



Many people in Friendswood, Pearland, and League City don’t realize they may be candidates for TMS until years after trying their first antidepressant. Some assume their symptoms aren’t “severe enough.” Others think they have to try every medication on the market before exploring an option like TMS. Unfortunately, misconceptions like these often delay care and relief.


TMS therapy (Transcranial Magnetic Stimulation) is a medication-free treatment that provides newfound hope to many people struggling with depression. Whether you’re in Pearland, League City, or Friendswood, we’re here to help you understand your options and to remind you that there is always a way forward.

What “Treatment-Resistant Depression” Really Means

The term “treatment-resistant depression” can sound intimidating. Many people assume it refers only to the most severe, debilitating forms of depression. In reality, it simply means that your depression hasn’t improved with standard treatment (usually antidepressant medication). It means your brain may need a different approach.


Clinically, treatment-resistant depression (or TRD) is often diagnosed when a person hasn’t experienced meaningful relief after trying one or more antidepressants at the appropriate dose and duration. The FDA uses this threshold as part of the criteria for TMS treatment, and many insurance companies do the same.


Those symptoms can show up in many ways.

  • Emotional signs like persistent sadness, worry, or a loss of interest.
  • Cognitive changes, such as difficulty concentrating or slowed thinking.
  • Physical symptoms include low energy, sleep disruptions, and changes in appetite.


When medication alone isn’t enough to address these symptoms, TMS provides a non-invasive option that targets the brain circuits involved in mood regulation.

Who Typically Benefits from TMS?

Woman eating from a white bowl in a kitchen, smiling.

TMS isn’t designed for one specific kind of person. As mentioned, it’s used for adults with Major Depressive Disorder who haven’t found relief with medication, or who simply can’t tolerate the side effects anymore.


Some patients also turn to TMS because medication side effects interfere with daily life. Maybe you’ve noticed weight changes, brain fog, sexual side effects, or emotional numbness. Maybe you feel “blunted” on antidepressants, as if your personality has been muted. These reactions are more common than most people realize and are valid reasons to explore alternative options.


In other cases, anxiety exists alongside depression, creating a more complex picture that medication alone doesn’t always solve.


Clinically, people who may benefit from TMS often share experiences such as:

  • A diagnosis of Major Depressive Disorder
  • Trying one or more antidepressants without meaningful relief
  • Not tolerating medication side effects
  • Co-occurring anxiety symptoms that complicate treatment
  • Feeling better with therapy, but not fully well
  • Experiencing brain fog, lethargy, or cognitive changes
  • Feeling frustrated by side effects or switching from one medication to the next

Who Might Not Be a Good Fit for TMS?

While TMS is a safe, well-tolerated treatment for many people, it isn’t the right fit for everyone. Individuals with non-removable metal or magnetic implants in or near the head, such as cochlear implants, aneurysm clips, or deep brain stimulators, and those with active seizure disorders or a history of seizures, are not a good fit for TMS.



It’s also important to understand that TMS is not an emergency or crisis intervention. It isn’t designed for immediate stabilization, hospitalization, or acute crisis support. Instead, it’s intended for outpatient treatment over several weeks.


Ultimately, the best way to determine whether TMS is appropriate is through a thorough evaluation with a qualified clinician. They will review your medical history, medications, symptoms, and safety considerations to ensure that treatment is both suitable and beneficial.

What TMS Feels Like and What to Expect

During treatment, you’ll sit in a comfortable chair while an electromagnetic coil rests lightly against your scalp. When the session begins, you may notice a tapping or knocking sensation in the area being targeted. It can feel unusual at first, but most patients adapt quickly. TMS therapy doesn’t involve anesthesia or sedation. You stay awake the entire time and can resume regular activities immediately after.


If fear of the unknown has been holding you back, it may help to know that TMS is not painful, disruptive, or destabilizing. It’s an approachable process that blends modern technology with a supportive, human-centered environment.

What to expect from TMS (simple timeline)

Most people describe TMS as approachable: you’re awake, sessions are outpatient, and progress tends to build gradually over several weeks.

  1. Consultation & eligibility review

    Medical history, current meds, symptoms, and safety screening.

    Often 1 visit
  2. Mapping / first session

    Coil positioning + settings are tailored to you.

    Clinic-guided setup
  3. Easy TMS sessions (outpatient procedure)

    You may feel tapping/knocking; no sedation; return to normal activities afterward.

    Multiple days/week
  4. Progress builds over time

    Many notice changes around weeks 2–4; a full course is commonly 6–8 weeks.

    2–8 weeks (typical)
  5. Next steps / maintenance (if needed)

    Some maintain gains without follow-ups; others benefit from periodic maintenance sessions.

    Personalized plan

How Long Does It Take to Notice a Change

TMS is not an instant treatment. Most patients begin noticing subtle improvements between 2 and 4 weeks into their treatment course. Those changes can look different for everyone. Some people first notice better sleep. Others feel a small increase in energy or motivation. Some start re-engaging with activities they used to enjoy.


A full course of TMS typically lasts 6 to 8 weeks, with sessions scheduled multiple days per week. This structure gives your brain time to form new pathways and adjust its activity patterns.


After completing a full TMS course, some individuals continue to maintain their progress on their own. Others benefit from periodic follow-up sessions or “maintenance TMS” to support long-term stability. Your doctor will work with you to determine what’s best throughout your treatment.


The most important thing to remember is that change with TMSis gradual and cumulative. The benefits build over time, often in ways patients don’t fully notice until they look back and realize how far they’ve come.

Get Evaluated for TMS Therapy in Friendswood, Pearland, or League City

If you’d like to explore TMS further, we offer free consultations to help you get the information you need. You can call our office or schedule an appointment online—whichever feels easier. This is your chance to ask questions, discuss concerns, and take the next step with confidence.


Living with depression can make it feel like you’ve run out of options, but you’re not stuck. Treatment-resistant depression is more common than people realize, and it doesn’t mean your condition is untreatable. It simply means it may be time to try something new.


If you’re wondering whether TMS might be right for you, the first step is a clinical evaluation. Talking with a clinician is the best way to determine whether TMS is the best path forward. A simple consultation can open the door to new possibilities and the hope you deserve.


We regularly work with patients from Friendswood, Pearland, League City, and the surrounding South Houston communities. Contact us today to learn how TMS can benefit you.

SCHEDULE A CONSULTATION

Review Our TMS Therapy FAQs

Answers based on the information on this page. Your clinician can confirm what applies to your medical history.

What does “treatment-resistant depression” mean?
It generally means your depression hasn’t improved enough with standard treatment—often after one or more antidepressants at an appropriate dose and duration.
Does TMS hurt or require sedation?
TMS doesn’t involve anesthesia or sedation. Many people feel a tapping/knocking sensation during sessions and adapt quickly.
How soon do people notice improvements?
Changes are typically gradual. Many notice subtle improvements around weeks 2–4 (sleep, energy, motivation), with benefits building over the full course.
How long is a full course of TMS?
A typical course lasts about 6–8 weeks, with sessions scheduled multiple days per week.
Who might not be a good fit for TMS?
People with certain non-removable metal/magnetic implants in or near the head (such as cochlear implants or aneurysm clips) or those with active seizure disorders/history of seizures may not be eligible. A clinician confirms safety during evaluation.
How to Know if TMS Therapy is Right for You

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